structure(list(y = structure(c(2L, 2L, 2L, 2L, 2L, 2L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 2L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 2L, 2L, 2L, 1L, 1L, 1L, 2L, 2L, 1L, 2L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 2L, 1L, 2L, 1L, 2L, 2L, 2L, 1L, 1L, 1L, 2L, 1L, 1L, 2L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 2L, 2L, 2L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 2L, 1L, 1L, 2L, 1L, 2L, 2L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 2L, 2L, 2L, 1L, 1L, 2L, 2L, 2L, 1L, 2L), levels = c("n", "y"), class = "factor"), ap = structure(c(2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L), levels = c("a", "p"), class = "factor"), hilo = structure(c(1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L), levels = c("hi", "lo"), class = "factor"), week = c(0L, 2L, 4L, 11L, 0L, 2L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 6L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 11L, 0L, 2L, 11L, 0L, 2L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 4L, 6L, 11L, 0L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 4L, 0L, 2L, 4L, 6L, 0L, 2L, 11L, 0L, 2L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 4L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 4L, 6L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 6L, 11L, 0L, 2L, 4L, 6L, 11L, 0L, 2L, 4L, 6L, 11L), ID = structure(c(1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 3L, 3L, 3L, 3L, 3L, 4L, 4L, 4L, 4L, 4L, 5L, 5L, 5L, 5L, 5L, 6L, 6L, 6L, 6L, 7L, 7L, 7L, 7L, 7L, 8L, 8L, 8L, 8L, 8L, 9L, 9L, 9L, 9L, 9L, 10L, 10L, 11L, 11L, 11L, 11L, 11L, 12L, 12L, 12L, 12L, 12L, 13L, 13L, 13L, 13L, 13L, 14L, 14L, 14L, 15L, 15L, 15L, 15L, 15L, 16L, 16L, 16L, 16L, 16L, 17L, 17L, 17L, 17L, 17L, 18L, 18L, 18L, 18L, 18L, 19L, 19L, 19L, 19L, 19L, 20L, 20L, 20L, 20L, 21L, 21L, 21L, 21L, 21L, 22L, 22L, 22L, 22L, 22L, 23L, 23L, 23L, 23L, 23L, 24L, 24L, 24L, 24L, 24L, 25L, 25L, 25L, 25L, 26L, 26L, 26L, 27L, 27L, 27L, 27L, 28L, 28L, 28L, 28L, 28L, 29L, 29L, 29L, 29L, 30L, 30L, 30L, 30L, 31L, 31L, 31L, 31L, 31L, 32L, 32L, 32L, 32L, 32L, 33L, 33L, 34L, 34L, 34L, 34L, 35L, 35L, 35L, 36L, 36L, 36L, 37L, 37L, 37L, 37L, 37L, 38L, 38L, 38L, 38L, 38L, 39L, 39L, 39L, 39L, 39L, 40L, 40L, 41L, 41L, 41L, 41L, 41L, 42L, 42L, 42L, 42L, 43L, 43L, 43L, 43L, 43L, 44L, 44L, 44L, 44L, 44L, 45L, 45L, 45L, 45L, 45L, 46L, 46L, 46L, 47L, 47L, 47L, 47L, 47L, 48L, 48L, 48L, 48L, 49L, 49L, 49L, 49L, 49L, 50L, 50L, 50L, 50L, 50L), levels = c("X01", "X02", "X03", "X04", "X05", "X06", "X07", "X08", "X09", "X10", "X11", "X12", "X13", "X14", "X15", "X16", "X17", "X18", "X19", "X20", "X21", "Y01", "Y02", "Y03", "Y04", "Y05", "Y06", "Y07", "Y08", "Y09", "Y10", "Y11", "Y12", "Y13", "Y14", "Z01", "Z02", "Z03", "Z05", "Z06", "Z07", "Z09", "Z10", "Z11", "Z14", "Z15", "Z19", "Z20", "Z24", "Z26"), class = "factor"), trt = structure(c(1L, 1L, 1L, 1L, 3L, 3L, 3L, 3L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 3L, 3L, 3L, 3L, 3L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 3L, 3L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 3L, 3L, 3L, 3L, 3L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 3L, 3L, 3L, 3L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 3L, 3L, 3L, 3L, 3L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 3L, 3L, 3L, 3L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 3L, 3L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 3L, 3L, 3L, 3L, 3L, 1L, 1L, 1L, 1L, 1L, 3L, 3L, 2L, 2L, 2L, 2L, 2L, 3L, 3L, 3L, 3L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 3L, 3L, 3L, 3L, 3L, 2L, 2L, 2L, 3L, 3L, 3L, 3L, 3L, 2L, 2L, 2L, 2L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L), levels = c("placebo", "drug", "drug+"), class = "factor")), class = "data.frame", row.names = c(NA, 220L))